The American model made her debut appearance in 2006, when she walked for Diane von Furstenberg at New York Fashion Week. She began receiving numerous modeling offers, and soon walked for top designers like Christian Lacroix, Oscar de la Renta, Marc Jacobs, Dolce & Gabbana, Versace Jeans, Etro, and D&G amongst others.
Erin Heatherton has walked on the world’s hottest runway at the annual Victoria's Secret Fashion Shows from 2008 – 2012, where she showcased some of the sexiest designs ever created by the lingerie brand.
Erin Heatherton landed her first ad campaign in 2006. After which, she was chosen to star in a new campaign for Michael Kors. In 2007, Mario Testino photographed her for D&G, and the same year she also modeled for Diesel and Valentino Couture advertisments. In 2008, Heatherton was photographed for Versace Jeans and Lord & Taylor ad campaigns. In addition to which, she posed for Karl Lagerfeld who photographed her for his eyewear collection. In 2011, the American model was chosen to feature as the face of John Galliano Underwear.
Heatherton likes watching and playing basketball whenever she gets a chance.