The Brazilian model made her runway debut in 1999 when she walked for Givenchy, Michael Kors and Versace during New York, Milan and Paris fashion weeks. She continued to present new collections one season after another and got the chance to work with the world's most known designers and brands. The list of designers who wanted Fontana on their catwalks includes Jean Paul Gaultier, Donna Karan, Vera Wang, Valentino, Balenciaga, Roberto Cavalli, Dolce & Gabbana, Salvatore Ferragamo and the list goes on and on.
Hermes was the first international brand that chose Fontana to be its new face in 2004. After the campaign, Fontana received a variety of other offers, and signed lots of advertising contracts. Along the years she featured as the face of Armani Jeans, Chanel, Colcci, Dolce & Gabbana, Emporio Armani, Oscar de la Renta, Revlon, Roberto Cavalli, H&M, Ralph Lauren and many others.
Isabeli Fontana has been married twice, and has one child from each relationship. She is still a very wanted model, and lately appeared on the covers of the Chinese and Spanish Vogue as well as the cover of the British Elle.